AIRR - ANZCA Institutional Research Repository
Skip navigation
Please use this identifier to cite or link to this item: http://hdl.handle.net/11055/483
Title: Opioid analgesic agents and cancer cell biology
Authors: Xie, N
Parat, M-O
Keywords: cancer
Cancer cell proliferation
Opioid receptor
Angiogenesis
Immunity
Migration
Issue Date: Sep-2015
Citation: 5: 278
Abstract: There is growing interest in the notion that perioperative factors may influence the long-term outcome of cancer surgery. Among these factors, pharmacologic agents including anesthetics and analgesics have been scrutinized for their potential effect on tumors. Opioids are particularly interesting in this context, as conflicting literature reports both pro- and anti-tumor effects for this class of drugs in every aspect of tumor growth and metastasis that has been examined. Cancer and non-cancer cells important to the tumor biology may be affected, as demonstrated using a variety of in vitro and preclinical models. More evidence is required to optimize the perioperative pain management of cancer surgery patients.
URI: http://hdl.handle.net/11055/483
DOI: 10.1007/s40140-015-0118-5
PubMed URL: https://link.springer.com/article/10.1007/s40140-015-0118-5
ISSN: 2167-6275
Journal Title: Current Anesthesiology Reports
Type: Journal Article
Affiliates: Australian and New Zealand College of Anaesthetists
Appears in Collections:Scholarly and Clinical

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.