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Please use this identifier to cite or link to this item: https://hdl.handle.net/11055/596
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dc.contributor.authorGlasford, NJen_US
dc.contributor.authorMyles, PSen_US
dc.contributor.authorBellomo, Ren_US
dc.date.accessioned2018-06-20T03:32:43Z-
dc.date.available2018-06-20T03:32:43Z-
dc.date.issued2012-02-
dc.identifier.citation25(1):102-10.en_US
dc.identifier.urihttp://hdl.handle.net/11055/596-
dc.description.abstractPURPOSE OF REVIEW: The role of fluid balance as an important contributor to patient morbidity and mortality in the peri-operative period is only now being understood. Numerous studies in disparate populations undergoing different surgeries suggest that. RECENT FINDINGS: There is wide disparity in fluid administration regimen between speciality, country, and clinician. Recent meta-analyses of published studies have shown that restrictive fluid administration strategies may improve patient-centred outcomes when compared to liberal regimens. Current evidence suggests a significant role for fluid accumulation in the development of peri-operative complications. Fluid balance is best achieved using goal-directed techniques. The evidence base is, at present, sub-optimal, with a paucity of level 1 evidence for clinical decision-making. SUMMARY: In the absence of level 1 evidence it is difficult to make firm recommendations about practice, though observational and single-centre data suggest a significant survival advantage may be conferred by the peri-operative administration of fluids to monitored physiological targets only. The Australian approach to peri-operative fluid management is to create level 1 evidence. To this end, the development of a large multicentre randomized controlled trial of peri-operative fluid administration is underway.en_US
dc.subjectRELIEFen_US
dc.titleThe Australian approach to peri-operative fluid balanceen_US
dc.typeJournal Articleen_US
dc.type.contentTexten_US
dc.identifier.journaltitleCurrent Opinion in Anesthesiologyen_US
dc.identifier.doi10.1097/ACO.0b013e32834decd7en_US
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/22113185en_US
dc.type.studyortrialReviews/Systematic Reviewsen_US
dc.identifier.studynameNCT01424150: REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery: RELIEF Study (RELIEF)en_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:Scholarly and Clinical
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