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Please use this identifier to cite or link to this item: http://hdl.handle.net/11055/825
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dc.contributor.authorHowarth Den_US
dc.contributor.authorBurstal Ren_US
dc.contributor.authorHayes Cen_US
dc.contributor.authorLan Len_US
dc.contributor.authorLantry Gen_US
dc.date.accessioned2018-12-14T02:06:44Z-
dc.date.available2018-12-14T02:06:44Z-
dc.date.issued1999-06-
dc.identifier.citation24(6):383-7en_US
dc.identifier.urihttp://hdl.handle.net/11055/825-
dc.description.abstractPURPOSE: Nuclear medicine techniques were used to show that the peripheral lymphatics are under autonomic control in much the same way as the blood vessels that supply the same anatomic region. METHODS: Three patients with complex regional pain syndrome type 1 (reflex sympathetic dystrophy) involving a lower extremity were evaluated using three-phase bone scintigraphy and peripheral lymphoscintigraphy. Each patient was treated with ipsilateral chemical lumbar sympathectomy, and lymphoscintigraphy was repeated within several days of the procedure. RESULTS: All three patients had evidence of decreased flow (compared with the contralateral extremity) to normal flow after ipsilateral sympathectomy. Bone scintigraphy, before and after sympathectomy, was difficult to interpret because of the effects of altered weight bearing. Two patients who had unilateral peripheral edema showed marked improvement after sympathectomy and increased lymphatic flow. CONCLUSIONS: Peripheral lymphatic function is controlled by the autonomic nervous system. In reflex sympathetic dystrophy, peripheral edema may be caused by an increased sympathetic stimulus to the lymphatics. Further study of this phenomenon may show that nuclear medicine studies, such as bone scintigraphy and lymphoscintigraphy, can be used to distinguish patients who will benefit from sympathectomy from those who will not, thereby obviating invasive testing and unnecessary invasive treatment.en_US
dc.subjectlymphoscintigraphyen_US
dc.subjectreflex sympathetic dystrophyen_US
dc.subjectnuclear medicineen_US
dc.subjectlymphatic systemen_US
dc.subjectradionuclide imagingen_US
dc.subjectlymphatic vesselsen_US
dc.subjectautonomic nervous systemen_US
dc.subjectsympathectomyen_US
dc.subjectlower extremityen_US
dc.subjectedemaen_US
dc.titleAutonomic regulation of lymphatic flow in the lower extremity demonstrated on lymphoscintigraphy in patients with reflex sympathetic dystrophy.en_US
dc.typeJournal Articleen_US
dc.type.contentTexten_US
dc.identifier.journaltitleClinical nuclear medicineen_US
dc.type.studyortrialCase Series and Case Reportsen_US
dc.contributor.anzcaHayes, Cen_US
Appears in Collections:Scholarly and Clinical

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