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Please use this identifier to cite or link to this item: https://hdl.handle.net/11055/857
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dc.contributor.authorDarvall JN,en_US
dc.contributor.authorGreentree K,en_US
dc.contributor.authorBraat MS,en_US
dc.contributor.authorStory DA,en_US
dc.contributor.authorLim WKen_US
dc.date2019-05-02-
dc.date.accessioned2019-06-12T00:51:59Z-
dc.date.available2019-06-12T00:51:59Z-
dc.identifier.citationJ Crit Care. 2019 May 2;52:193-199.en_US
dc.identifier.urihttp://hdl.handle.net/11055/857-
dc.description.abstractAbstract PURPOSE: Frailty in critical illness is common and associated with poor outcomes, however little is known about contributing factors. We compared the Clinical Frailty Scale (CFS) with a multi-dimensional validated tool, the Edmonton Frail Scale (EFS), and investigated which health domains are affected by frailty in ICU. MATERIALS AND METHODS: This prospective cohort study enrolled patients aged ≥50 years admitted between February-June 2017, comparing the CFS and EFS using Spearman correlation and Kappa coefficients, assessing frailty status across health domains, and examining outcomes including mortality. RESULTS: One hundred and sixty patients were enrolled, 33.8% were frail. Frail patients had greater in-hospital and 6-month mortality [25.9% vs. 8.5%; adjusted OR (95% CI) = 3.31 (1.17, 9.39), p = .024; and 40.4% vs. 17.3%; OR (95% CI) = 2.84 (1.18, 6.83), p = .020 respectively]. CFS and EFS scales were highly correlated [Spearman correlation coefficient = 0.85 (95% CI 0.81-0.88)], with high agreement [kappa coefficient = 0.78 (95% CI: 0.68-0.88)]. Frail patients had worse health status across the spectrum of frailty domains, in particular functional dependence, malnutrition, and prior hospital admissions. CONCLUSIONS: Frailty in the critically ill affects a range of health deficits, adequately measured via the CFS.en_US
dc.subjectCritical care;en_US
dc.subjectFrailtyen_US
dc.subjectRisk assessmenten_US
dc.titleContributors to frailty in critical illness: Multi-dimensional analysis of the Clinical Frailty Scaleen_US
dc.typeJournal Articleen_US
dc.type.contentTexten_US
dc.identifier.journaltitleJ Crit Careen_US
dc.identifier.doi10.1016/j.jcrc.2019.04.032en_US
dc.description.affiliatesDepartments of Intensive Care and Anaesthesia/Pain Management, Royal Melbourne Hospital, Melbourne, Australia; Centre for Integrated Critical Care, The University of Melbourne, Melbourne, Australia. Electronic address: jai.darvall@mh.org.au.en_US
dc.description.affiliatesDepartments of Intensive Care and Anaesthesia/Pain Management, Royal Melbourne Hospital, Melbourne, Australia.en_US
dc.description.affiliatesCentre for Epidemiology and Biostatistics, Melbourne Clinical and Translational Science Platform, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.en_US
dc.description.affiliatesCentre for Integrated Critical Care, The University of Melbourne, Melbourne, Australia.en_US
dc.description.affiliatesDepartment of Medicine, University of Melbourne, Melbourne, Australia.en_US
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/?term=Contributors+to+frailty+in+critical+illness%3A+Multi-dimensional+analysis+of+the+Clinical+Frailty+Scale.en_US
dc.type.studyortrialClinical Trialen_US
dc.contributor.anzcaaddGreentree, K (seems likely)en_US
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:Scholarly and Clinical
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