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https://hdl.handle.net/11055/857
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DC Field | Value | Language |
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dc.contributor.author | Darvall JN, | en_US |
dc.contributor.author | Greentree K, | en_US |
dc.contributor.author | Braat MS, | en_US |
dc.contributor.author | Story DA, | en_US |
dc.contributor.author | Lim WK | en_US |
dc.date | 2019-05-02 | - |
dc.date.accessioned | 2019-06-12T00:51:59Z | - |
dc.date.available | 2019-06-12T00:51:59Z | - |
dc.identifier.citation | J Crit Care. 2019 May 2;52:193-199. | en_US |
dc.identifier.uri | http://hdl.handle.net/11055/857 | - |
dc.description.abstract | Abstract PURPOSE: Frailty in critical illness is common and associated with poor outcomes, however little is known about contributing factors. We compared the Clinical Frailty Scale (CFS) with a multi-dimensional validated tool, the Edmonton Frail Scale (EFS), and investigated which health domains are affected by frailty in ICU. MATERIALS AND METHODS: This prospective cohort study enrolled patients aged ≥50 years admitted between February-June 2017, comparing the CFS and EFS using Spearman correlation and Kappa coefficients, assessing frailty status across health domains, and examining outcomes including mortality. RESULTS: One hundred and sixty patients were enrolled, 33.8% were frail. Frail patients had greater in-hospital and 6-month mortality [25.9% vs. 8.5%; adjusted OR (95% CI) = 3.31 (1.17, 9.39), p = .024; and 40.4% vs. 17.3%; OR (95% CI) = 2.84 (1.18, 6.83), p = .020 respectively]. CFS and EFS scales were highly correlated [Spearman correlation coefficient = 0.85 (95% CI 0.81-0.88)], with high agreement [kappa coefficient = 0.78 (95% CI: 0.68-0.88)]. Frail patients had worse health status across the spectrum of frailty domains, in particular functional dependence, malnutrition, and prior hospital admissions. CONCLUSIONS: Frailty in the critically ill affects a range of health deficits, adequately measured via the CFS. | en_US |
dc.subject | Critical care; | en_US |
dc.subject | Frailty | en_US |
dc.subject | Risk assessment | en_US |
dc.title | Contributors to frailty in critical illness: Multi-dimensional analysis of the Clinical Frailty Scale | en_US |
dc.type | Journal Article | en_US |
dc.type.content | Text | en_US |
dc.identifier.journaltitle | J Crit Care | en_US |
dc.identifier.doi | 10.1016/j.jcrc.2019.04.032 | en_US |
dc.description.affiliates | Departments of Intensive Care and Anaesthesia/Pain Management, Royal Melbourne Hospital, Melbourne, Australia; Centre for Integrated Critical Care, The University of Melbourne, Melbourne, Australia. Electronic address: jai.darvall@mh.org.au. | en_US |
dc.description.affiliates | Departments of Intensive Care and Anaesthesia/Pain Management, Royal Melbourne Hospital, Melbourne, Australia. | en_US |
dc.description.affiliates | Centre for Epidemiology and Biostatistics, Melbourne Clinical and Translational Science Platform, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia. | en_US |
dc.description.affiliates | Centre for Integrated Critical Care, The University of Melbourne, Melbourne, Australia. | en_US |
dc.description.affiliates | Department of Medicine, University of Melbourne, Melbourne, Australia. | en_US |
dc.description.pubmeduri | https://www.ncbi.nlm.nih.gov/pubmed/?term=Contributors+to+frailty+in+critical+illness%3A+Multi-dimensional+analysis+of+the+Clinical+Frailty+Scale. | en_US |
dc.type.studyortrial | Clinical Trial | en_US |
dc.contributor.anzcaadd | Greentree, K (seems likely) | en_US |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.openairetype | Journal Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
Appears in Collections: | Scholarly and Clinical |
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